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Human MCP-1/MCAF ELISA KIT is used for quantitative determination of human monocyte chemotactic protein 1/monocyte chemotactic and activating factor (MCP-1/MCAF) concentrations in serum, plasma, urine, saliva, cerebrospinal fluid (CSF), ascitic fluid, cell culture supernates, tissue homogenates.
Monocyte chemoattractant protein 1 (MCP-1) belongs to a small cytokine of the CC chemokine family. Studies have shown that MCP-1 is an important proinflammatory cytokine. Monocytes, macrophages, fibroblasts, vascular endothelial cells, B cells, smooth muscle cells, etc. can all secret MCP-1 when inflammation occurs in the body. and MCP-1 has a specific chemotactic activation effect on monocytes / macrophages. In particular, it plays an important role in the occurrence and development of rheumatoid arthritis, glomerulonephritis, atherosclerosis, acute coronary syndrome, deep vein thrombosis and other diseases.
CCL2, chemokine (C-C motif) ligand 2, C-C motif chemokine 2, GDCF 2, GDCF2, MCP-1, MCAF, Human monocyte chemotactic protein 1, monocyte chemotactic and activating factor