SARS-CoV-2 CPE Assay
Various pathological cell alterations triggered by eukaryotic viruses are referred to as the Cytopathic Effect (CPE). By CPE, viral proliferation could be estimated through observable changes in cultured cells under a light microscope. Creative Biolabs now provides top-rated antiviral assay services based on cytopathic effect (CPE) to help you screen potentially antiviral compounds.
SARS-CoV-2 Spike-pseudovirus Based Neutralization Assay Services
Creative Biolabs uses HIV-1 containing a luciferase reporter gene as a backbone plasmid, and co-transfects 293 cells with a plasmid expressing the SARS-CoV-2 spike protein to package a spike-pseudovirus with SARS-CoV-2 spike protein expressing on its surface and containing luciferase reporter gene inside. In combination with our proprietary ACE2-overexpressing cells, Creative Biolabs now provides neutralization assay services for our customers.
Protease Inhibitor Assay of SARS-CoV-2
The main protease of SARS-CoV-2 is considered to be essential for viral replication, and therefore is considered a promising target for COVID-19 antiviral therapy. To find and validate potent inhibitors for SARS-CoV-2 protease, Creative Biolabs provides protease assay service to help speed up the development of therapeutics to conquer COVID-19.
SARS-CoV-2 Virus-like Particles (VLPs)
Creative Biolabs has developed the SARS-CoV-2 VLP successfully and now offers high-quality VLP production services for our worldwide customers.
Cell Lines for SARS-CoV-2 Research
As a leading CRO company in the industry, Creative Biolabs continuously provides researchers with high-quality basic research tools and highly-praised technical services, helping thousands of researchers complete their research tasks in biomedicine. We have developed a series of cell lines for COVID-19 research, including ACE2-enhanced or knockout (KO) cell lines, TMPRSS2-enhanced or knockout (KO) cell lines, and so on.
Working around the clock, we have developed a series of aptamers with high affinity for SARS-CoV-2 spike protein S1 and N protein and ensure that they can bind to the target protein in SPR detection. Contact us to find more information and explore how aptamers can help in your research.