Cell Lines for SARS-CoV-2 Research

As a leading CRO company in the industry, Creative Biolabs continuously provides researchers with high-quality basic research tools and highly-praised technical services, helping thousands of researchers complete their research tasks in biomedicine. We have developed a series of cell lines for COVID-19 research, including ACE2-enhanced or knockout (KO) cell lines, TMPRSS2-enhanced or knockout (KO) cell lines, and so on.

ACE2-overexpressing Stable Cell Lines

Spike-expressing Stable Cell Lines

The spike protein plays a key role in inducing neutralizing antibody and T cell responses and protective immunity during infection with SARS-CoV-2. Creative Biolabs is developing stable cell lines that can stably express Spike protein of SARS-CoV-2.

CAT Product Name CAT Product Name
VCeL-Wyb030 Spike-CHO Stable Cell Line VCeL-Wyb031 Spike-HEK293 Stable Cell Line
COSX-0422-SX5 Spike-HEK293T Stable Cell Line

Knockout Cell Line

CAT Product Name Product Overview
VCeL-Wyb033 ΔhACE2-HEK293T Cell Line hACE2 Knockout HEK293T Cell Line
VCeL-Wyb034 ΔTMPRSS2-HEK293T Cell Line TMPRSS2 Knockout HEK293T Cell Line
VCeL-Wyb035 ΔhACE2-HEK293 Cell Line hACE2 Knockout HEK293 Cell Line
VCeL-Wyb036 ΔTMPRSS2-HEK293 Cell Line TMPRSS2 Knockout HEK293 Cell Line
VCeL-Wyb037 ΔhACE2-HeLa Cell Line hACE2 Knockout HeLa Cell Line
VCeL-Wyb038 ΔTMPRSS2-HeLa Cell Line TMPRSS2 Knockout HeLa Cell Line

Other SARS-CoV-2 Research Related Cell Line

  • ACE2 Enhanced Cell Line
CAT Product Name Product Overview
VCeL-Wyb041 ACE2 enhanced BEWO Cell Line ACE2 enhanced human choriocarcinoma cell
VCeL-Wyb042 ACE2 enhanced HaCaT Cell Line ACE2 enhanced immortalized human Keratinocyte cell
VCeL-Wyb043 ACE2 enhanced HepG2 Cell Line ACE2 enhanced human hepatocellular carcinoma cell
VCeL-Wyb044 ACE2 enhanced NB-4 Cell Line ACE2 enhanced human acute promyelocytic leukemia cell
VCeL-Wyb045 ACE2 enhanced RPMI-8226 Cell Line ACE2 enhanced human Myeloma cell
VCeL-Wyb046 ACE2 enhanced SH-SY5Y Cell Line ACE2 enhanced human neuroblastoma cell
  • TMPRSS2 Enhanced Cell Lines
CAT Product Name Product Overview
VCeL-Wyb047 TMPRSS2 enhanced Caco-2 Cell Line TMPRSS2 enhanced human epithelial colorectal adenocarcinoma cell
VCeL-Wyb048 TMPRSS2 enhanced MCF-7 Cell Line TMPRSS2 enhanced human breast cancer cell
VCeL-Wyb049 TMPRSS2 enhanced SK-BR-3 Cell Line TMPRSS2 enhanced human breast cancer cell
VCeL-Wyb050 TMPRSS2 enhanced T-47D Cell Line TMPRSS2 enhanced human breast cancer cell
  • ACE2 and TMPRSS2 Co-Enhanced Cell Line
CAT Product Name Product Overview
VCeL-Wyb051 ACE2-TMPRSS2 co-enhanced RT4 Cell Line ACE2-TMPRSS2 co-enhanced human bladder carcinoma cell
VCeL-Lsx001 TMPRSS2 enhanced VeroE6 Cell Line VeroE6 cells stably express transmembrane serine protease TMPRSS2.

Commonly Used Cell Lines for SARS-CoV-2 Research

CAT Product Name CAT Product Name
VCeL-Wyb003 A549 VCeL-Wyb012 MDCK
VCeL-Wyb004 BHK-21 VCeL-Wyb014 PK-15
VCeL-Wyb006 CaCo-2 VCeL-Wyb016 VERO
VCeL-Wyb008 HEK293 VCeL-Wyb039 HEK293T
VCeL-Wyb010 HuH7 VCeL-Wyb040 U937
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