Human IP-10 ELISA KIT (CAT#: VCye-Wyb010)

• Product Overview
• Human IP-10 ELISA KIT is used for quantitative determination of human interferon-inducible protein 10 (IP-10) concentrations in serum, plasma, tissue homogenates.

• Sensitivity
• 7.8 pg/mL

• Target
• SARS-CoV-2

• Speicies
• Human

• Contents
• Assay plate (12 x 8 coated Microwells), Standard, Biotin-antibody, HRP-avidin, Biotin-antibody Diluent, HRP-avidin Diluent, Sample Diluent, Wash Buffer (25 x concentrate), TMB Substrate, Stop Solution, Adhesive Strip (For 96 wells).

• Testing Principle
• Quantitative ELISA

• Detection Wavelength
• 450 nm

• Detection Range
• 31.25 pg/mL-2000 pg/mL

• Precision
• Intra-assay Precision: CV% < 8%
  Inter-assay Precision: CV% < 10%

• Average Recovery
• 0.92

• Sample Types
• Serum, plasma, tissue homogenates

• Sample Volume
• 50-100 μL

• Storage
• Store at 2-8°C.

• Introduction
• The receptor for IP-10 (interferon-inducible protein-10) is CXCR3. IP-10 is mainly derived from monocytes / K phagocytes and T lymphocytes, and its variants can enhance receptor activity. IP-10 is closely related to CXCLll / I-IAC and can be converted into each other. During the inflammatory reaction such as viral infection, the concentration of IP-10 in various systems (such as nervous system, liver and spleen, etc.) may increase to varying degrees, and also significantly increase in transplant rejection. Given its unique role, IP-10 targeted therapy is expected to prevent the clinical progression of certain diseases.

• Alternative Names
• Interferon gamma induced factor MOB1, chemokine (C-X-C motif) ligand 10, CXCL10, Interferon gamma induced protein 10, interferon-inducible protein 10, IP-10