Interferon is the earliest discovered cytokine. It is a low-molecular-weight multifunctional glycoprotein produced by viruses and interferon inducers acting on host cells. It is named for its ability to interfere with viral infection and replication. Interferon can be divided into type Ⅰ and type Ⅱ interferon. Type Ⅰ interferon includes IFN-α, IFN-β, IFN-κ, etc. IFN-γ belongs to type Ⅱ interferon, produced by activated T cells and NK cells. It can activate macrophages, promote the expression of MHC molecules, induce Th1 cell differentiation, and inhibit Th2 cell differentiation.
IFNG, IFN-γ, IFN gamma, Type II Interferon, Interferon, Interferon γ