Chloroquine (CAT#: Vinh-Wyb013)

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Vinh-Wyb013
For Research Use Only. We do not provide services or products directly for patients.

  • Product Overview
  • Molecular Formula: C18H26ClN3; Molecular Weight: 319.87 g.mol-1
  • CAS No.
  • 58175-87-4
  • Target
  • SARS-CoV-2
  • Molecular Formula
  • C18H26ClN3
  • Molecular Weight
  • 319.87 g.mol-1
  • Purity
  • >98%
  • Introduction
  • Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Chloroquine also is an inhibitor of toll-like receptors (TLRs). Chloroquine can also combine with heme to form a toxic heme-Chloroquine complex, which can inhibit vacuolar phospholipase, increase vacuolar pH, inhibit vacuolar protease and heme polymerase activity, thereby inhibiting the breakdown of trophozoite hemoglobin. As a chemotherapeutic agent for clinical treatment of malaria. Chloroquine can bind DNA and inhibit DNA replication and RNA synthesis to cause cell death.

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