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Product Overview
Human ACE2, Rabbit anti-ACE2 IgG Antibody.
Target
ACE2
Source
Rabbit
Clonality
PAb
Immunogen
Human ACE2 protein
Specificity
Human, Mouse, Rat ACE2
Type
Antibody
Purification
Antigen Affinity
Form
Liquid
Buffer Solution
0.1% Sodium Azide, 50% Glycerol, pH 7.3.
Applications
Used for ELISA, WB.
Storage
Store at -20°C or -80°C
Introduction
Angiotensin-converting enzyme 2 (ACE2) regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Abundant evidence demonstrated that ACE2 plays physiological and pathological role in the cardiovascular, renal and respiratory systems as well as blood pressure control. Ang-(1-7) is considered as major biologically active product of ACE2. ACE2's physiological role has been implicated in hypertension, cardiac function, heart function and diabetes, and as a receptor of the SARS-CoV (severe acute respiratory syndrome coronavirus). Moreover, ACE2 has been identified as a key SARS-coronavirus receptor and plays a protective role in severe acute respiratory syndrome (SARS) pathogenesis.