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Product Overview
Anti-ACE2 (Rat) Monoclonal Antibody, Mouse source, for ELISA(Cap).
Target
ACE2
Source
Mouse
Clonality
MAb
Immunogen
Recombinant rat ACE2 protein
Specificity
Rat ACE2
Type
Antibody
Conjugate
Unconjugated
Purification
Protein A
Form
Liquid
Buffer Solution
0.2 μm filtered solution in PBS
Applications
Used for ELISA(Cap).
Storage
Store at 2 °C to 8 °C short term, -20 °C long term.
Introduction
Angiotensin-converting enzyme 2 (ACE2) regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Abundant evidence demonstrated that ACE2 plays physiological and pathological role in the cardiovascular, renal and respiratory systems as well as blood pressure control. Ang-(1-7) is considered as major biologically active product of ACE2. ACE2's physiological role has been implicated in hypertension, cardiac function, heart function and diabetes, and as a receptor of the SARS-CoV (severe acute respiratory syndrome coronavirus). Moreover, ACE2 has been identified as a key SARS-coronavirus receptor and plays a protective role in severe acute respiratory syndrome (SARS) pathogenesis.