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2-[4-(2-hydroxyethoxy)-3,5-dimethylphenyl]-5,7-dimethoxy-4(3H)-quinazolinone, BET bromodomain antagonist
>98% by HPLC
Store at -20°C.
RVX-208 also knows as Apabetalone is a potent selective inhibitor of the BET bromodomains. The compound has been thoroughly studied for its role against some key viruses such as HIV-1. By interacting with key bromodomain proteins BRD2 and BRD4, RVX-208 may inhibit the interaction of these proteins with the SARS-CoV-2 protein E, aiding in stopping some key viral processes such as cell entry and replication.