Remdesivir (CAT#: Vinh-Wyb012)

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Vinh-Wyb012
For Research Use Only. We do not provide services or products directly for patients.

  • Product Overview
  • Molecular Formula: C27H35N6O8P; Molecular Weight: 602.58 g.mol-1
  • CAS No.
  • 1809249-37-3
  • Target
  • SARS-CoV-2
  • Molecular Formula
  • C27H35N6O8P
  • Molecular Weight
  • 602.58 g.mol-1
  • Purity
  • >98%
  • Introduction
  • Remdesivir is a cyano-substituted adenosine nucleotide analog prodrug and shows broad-spectrum antiviral activity against several RNA viruses. In HAE cells, Remdesivir has an EC50 value of 74 nM for SARS-CoV and MERS-CoV, and 30 nM for murine hepatitis virus in delayed brain tumor cells. In vitro experiments and animal model data indicate that remdesivir inhibits SARS-CoV, MERS-CoV, and Ebola virus by inhibiting RNA-dependent RNA polymerase (RdRp). In vitro cell experiments showed that the half effective concentration (EC50) of remdesivir for the new coronavirus was 0.77 μmol·L-1.

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