Recombinant ACE2 Protein (aa 18-740) [His-Avi] (CAT#: VReP-095SX)
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VReP-095SX
For Research Use Only. We do not provide direct services or products for patients.
Product Overview
Human recombinant ACE2 Protein [His-Avi]
Source
HEK293 Cells
Tag
Avi-His
Target
ACE2
Type
Recombinant Proteins
Applications
Functional ELISA, etc.
Formulation
50 mM Tris, 150 mM NaCl, pH7.5.
Purity
> 90% by SDS-PAGE.
Product Form
Lyophilized
Storage
Store at -20°C to -80°C.
Introduction
Angiotensin-converting enzyme 2 (ACE2) regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Abundant evidence demonstrated that ACE2 plays physiological and pathological role in the cardiovascular, renal and respiratory systems as well as blood pressure control. Ang-(1-7) is considered as major biologically active product of ACE2. ACE2's physiological role has been implicated in hypertension, cardiac function, heart function and diabetes, and as a receptor of the SARS-CoV (severe acute respiratory syndrome coronavirus). Moreover, ACE2 has been identified as a key SARS-coronavirus receptor and plays a protective role in severe acute respiratory syndrome (SARS) pathogenesis.