Human ACE2 ELISA Detection Kit (CAT#: VCok-Wyb018)

• Product Overview
• The Human ACE2 ELISA Detection Kit is a sandwich ELISA-based assay for the quantitative detection of human ACE2 in serum, plasma, cell culture supernates.

• Target
• ACE2

• Specificity
• Human ACE2

• Contents
• Assay plate (12 x 8 coated Microwells); Standard; 100 x Biotin-antibody; 100 x HRP-avidin; Biotin-antibody Diluent; HRP-avidin Diluent; Sample Diluent; 25 x Wash Buffer; TMB Substrate; Stop Solution; Adhesive Strip.

• Testing
• ACE2

• Testing Principle
• Quantitative sandwich ELISA

• Conjugate
• Biotin, HRP

• Linear Range
• 0.156 ng/mL-10 ng/mL

• Sensitivity
• 0.039 ng/Ml

• Applications
• Qualitative detection of human ACE2 in serum, plasma, cell culture supernates.

• Storage
• Store at 4°C

• Introduction
• Angiotensin-converting enzyme 2 (ACE2) regulates the renin angiotensin system (RAS) by counterbalancing ACE activity. Abundant evidence demonstrated that ACE2 plays physiological and pathological role in the cardiovascular, renal and respiratory systems as well as blood pressure control. Ang-(1-7) is considered as major biologically active product of ACE2. ACE2's physiological role has been implicated in hypertension, cardiac function, heart function and diabetes, and as a receptor of the SARS-CoV (severe acute respiratory syndrome coronavirus). Moreover, ACE2 has been identified as a key SARS-coronavirus receptor and plays a protective role in severe acute respiratory syndrome (SARS) pathogenesis.

• Alternative Names
• Angiotensin-converting enzyme 2; ACE2)