Human CTSB ELISA Detection Kit (CAT#: VCok-Wyb021)
Product Overview
The Human CTSB ELISA Detection Kit is a sandwich ELISA-based assay for the quantitative detection of human cathepsin B in serum, plasma, tissue homogenates.
Target
SARS-CoV-2
Specificity
Human CTSB
Contents
Assay plate (12 x 8 coated Microwells); Standard; 100 x Biotin-antibody; 100 x HRP-avidin; Biotin-antibody Diluent; HRP-avidin Diluent; Sample Diluent; 25 x Wash Buffer; TMB Substrate; Stop Solution; Adhesive Strip.
Testing Principle
Quantitative sandwich ELISA
Conjugate
Biotin, HRP
Linear Range
0.312 ng/mL-20 ng/mL
Sensitivity
0.078 ng/mL
Applications
Qualitative detection of human CTSB in serum, plasma, tissue homogenates.
Storage
Store at 4°C
Introduction
Cathepsin B (CTSB) is a lysosomal cysteine protease consisting of disulfide-linked dimers of the heavy and light chains, both of which are produced by a single protein precursor. It is also called amyloid precursor protein secretase and is involved in the proteolytic process of amyloid precursor protein (APP). The encoded protein is a member of the C1 family of peptidases, and its overexpression is associated with esophageal adenocarcinoma and other tumors. The gene has been found to have at least five transcript variants encoding the same protein. In addition, studies have shown that the enzyme may have pro-apoptotic functions and can degrade extracellular matrix proteins.
Alternative Names
Human cathepsin B; CTSB; cysteine protease; Preprocathepsin B; Amyloid precursor protein secretase